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Complexity of science. Simplicity of skincare.

In the world of anti-aging and advanced skincare, the most powerful solution is a solution that comes from you, and we’ve developed a revolutionary serum that is all about you. Leading the market, Aesthetics Biomedical® Inc. has developed a patented personalized topical take-home cosmetic product that utilizes Platelet Rich Plasma (PRP), supported by clinical results. Aesthetics Biomedical® is proud to introduce SoME® Skincare to the clinical community for point of care physician use.

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About SoME® Skincare

The use of PRP in aesthetics has grown world-wide and inspired the development of the unique take-home cosmetic formulation SoME® Skincare. SoME® Skincare is a rejuvenating topical skincare product that uses a proprietary blend of ingredients combined by your physician with your own Platelet Rich Plasma (PRP) to give you a truly personalized cosmetic experience.

Platelet Rich Plasma Constituents

The field of orthopedics was the first to discover the true healing and regenerative properties of growth factors derived from Platelet Rich Plasma (PRP). Growth factors or cytokines are proteins that occur naturally and stimulate our cells to reproduce themselves. Growth factors bind to receptors on the cell’s surface and it’s there that they begin their work, all throughout the body.
  • Normal platelet count in human blood is 150,000-350,000/microliter.
  • PRP is defined as concentrated platelets in a small volume of plasma that contain biomolecules such as growth factors, clotting factors, platelet derived exosomes, and other key rejuvenation factors.
  • 7 Growth factors in PRP: platelet derived growth factors (PDGFaa, PDGFbb, PDGFab), transforming growth factors (TGF-b2, TGFb2), vascular endothelial growth factor (VEGF), and epithelial growth factor (EGF).
  • Growth factors are found within a normal clot composed of fibrin, fibronectin, and vitronectin, which are cell adhesion molecules required for cell migration, as seen in wound healing.
SoME® Skincare Products in Hand
SoME® Skincare Products Fridge

The future of personalized skincare

SoME® Skincare + PRP is a skin rejuvenating treatment that uses all-natural ingredients to reduce the appearance of fine lines and wrinkles, enhances skin tone and texture, discoloration, puffiness, and darkness around the eyes. What happens next is your stunningly beautiful skin is revealed for you and the world to see.

Until now, there has never been an autologous topical skincare product with proven results. SoME® Skincare + PRP uses the body’s own regenerative properties to stimulate natural collagen and elastin for visibly renewed firmness and luminosity. The cosmetic serum was formulated and rigorously tested by Aesthetics Biomedical® Inc. to ensure that when combined with an individual’s PRP, by your physician, the platelets are preserved for optimal effect upon use. SoME® Skincare proprietary base preserves platelet components allowing the product to remain efficacious over the course of three months.

  • Clinical, Histological, and Molecular Endpoints Demonstrated Significant Results for SoME® Skincare Base Serum + PRP vs. SoME® Skincare Base Serum.
  • Skincare Alone.
  • Aesthetically-Pleasing, Well-Tolerated, No Adverse Events.
  • 100% of Study Subjects Stated They Would Purchase SoME® Skincare.
  • No Discomfort with SoME® Skincare Applications vs. PRP Injections.

SoME® Skincare Ingredients

The field of orthopedics was the first to discover the true healing and regenerative properties of growth factors derived from Platelet Rich Plasma (PRP). Growth factors or cytokines are proteins that occur naturally and stimulate our cells to reproduce themselves. Growth factors bind to receptors on the cell’s surface and it’s there that they begin their work, all throughout the body.

Platelet Rich Plasma (PRP)

Platelet Rich Plasma (PRP) is an all-natural derivative of your blood that contains a high volume of growth factors shown to be effective in aesthetic skincare and wound healing.

Botanical Preservation System

Lonicera japonica and lonicera caprifolium flower extracts are honeysuckle extracts added to your SoME® Skincare serum to keep it fresh and preserved.

Specialty Ingredients

Hyaluronic acid is a protein found in your body that attracts moisture to keep your tissues hydrated and moisturized.

Novel Skin Nutrient System/Complex

Glucose, sodium citrate, sodium acetate, sodium bicarbonate, sodium chloride, potassium phosphate, potassium chloride, and magnesium chloride provide essential nutrients that are needed to keep your skin healthy and fresh.

Botanical and Antioxidant Complexes

Avocado oil (Persea Gratissima) is rich in fatty acids, which naturally moisturizes the skin. Marshmallow root extract (Althaea Officinalis) lowers swelling and kills bacteria. D-alpha tocopheryl acetate (Vitamin E) contains antioxidant and anti-inflammatory properties that are essential for healthy skin.

Clinical Study Outcomes

Two clinical studies (60 days & 120 days), 20 patients per study demonstrated excellent tolerability, no adverse events.

SoME® Skincare + PRP demonstrated significant identifiable clinical improvement in softness, firmness, luminosity (brightness), radiance (shine), improvement with hyperpigmentation at four weeks with enhanced performance over eight-week period as assessed by the PI.

Study participants rated enhanced cosmetic performance in the same skin conditions as noted by the PI.

98% Patient satisfaction.

Two-year shelf life of SoME® Skincare base.

Value for Topical PRP in Facial Rejuvenation

Pilot Study: Autologous platelet-rich plasma used in a topical cream for facial rejuvenation
Graph 1
Graph 2

Method:

Split-face, randomized, investigator-blinded

Stats:

20 females/males; age 30-60; 3 to 6 on Griffin Scale Patients were evaluated by investigators at 8 and 16 weeks

Products:

Base Serum, Base Serum + PRP and sunscreen SPF 30

RET PEG Analysis Contron
RET PEG Analysis Treatment

Ret Peg Analysis

Rete peg analysis is a ratio of the stratum basale to the stratum granulosum.

The higher the ratio, the more rete pegs present. The red line traces the dermal epidermal junction. The wavier the line, the healthier the skin.

The left panel is the control sample. The right panel is the treatment sample.

Collagen Analysis Control
Collagen Analysis Treatment

Collagen Type 1

Collagen I analysis uses color deconvolution algorithms to determine the staining intensity of the DAB color for collagen I.

The left panel is the control sample. The right panel is the treatment sample.

Elastin Analysis Control
Elastin Analysis Treatment

Elastin Analysis

Elastin analysis uses color deconvolution algorithms to determine the staining intensity of the Color Markup color for elastin.

The left panel is the control sample. The right panel is the treatment sample.

Color Markup of the Image

  • Yellow = Weak Positive
  • Orange = Positive
  • Red = Highly Positive
  • Blue = Negative

Before & After Results

Photos courtesy of Dr. Zoe Diana Draelos, MD
*Individual results may vary